A mathematical model of cellular immune response to leukemia

نویسندگان

چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Analysis of Response Robustness for a Multi-Objective Mathematical Model of Dynamic Cellular Manufacturing

The multi-objective optimization problem is the main purpose of generating an optimal set of targets known as Pareto optimal frontier to be provided the ultimate decision-makers. The final selection of point of Pareto frontier is usually made only based on the goals presented in the mathematical model to implement the considered system by the decision-makers. In this paper, a mathematical model...

متن کامل

A Mathematical Model of Immune Response to Tumor Invasion

Recent experimental studies by Diefenbach et al. [1] have brought to light new information about how the immune system of the mouse responds to the presence of a tumor. In the Diefenbach studies, tumor cells are modified to express higher levels of immune stimulating NKG2D ligands. Experimental results show that sufficiently high levels of ligand expression create a significant barrier to tumor...

متن کامل

Cellular response to ionizing radiation: A microRNA story

MicroRNAs (miRNAs) represent a class of small non-coding RNA molecules that regulate gene expression at the post-transcriptional level. They play a crucial role in diverse cellular pathways. Ionizing radiation (IR) is one of the most important treatment protocols for patients that suffer from cancer and affects directly or indirectly cellular integration. Recently it has been discovered that mi...

متن کامل

B Cell Chronic Lymphocytic Leukemia - A Model with Immune Response

B cell chronic lymphocytic leukemia (B-CLL) is known to have substantial clinical heterogeneity. There is no cure, but treatments allow for disease management. However, the wide range of clinical courses experienced by B-CLL patients makes prognosis and hence treatment a significant challenge. In an attempt to study disease progression across different patients via a unified yet flexible approa...

متن کامل

Mathematical model of a three-stage innate immune response to a pneumococcal lung infection.

Pneumococcal pneumonia is a leading cause of death and a major source of human morbidity. The initial immune response plays a central role in determining the course and outcome of pneumococcal disease. We combine bacterial titer measurements from mice infected with Streptococcus pneumoniae with mathematical modeling to investigate the coordination of immune responses and the effects of initial ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Mathematical and Computer Modelling

سال: 2005

ISSN: 0895-7177

DOI: 10.1016/j.mcm.2005.05.003